Partek Flow Documentation

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Includes performance optimizations and fixes for improved speed and usability of Partek® Flow® software. To upgrade to this version, please follow the steps outlined in our Installation Guide.

10.0.21.1116

  • Sped up h5 file import
  • Sped up transfer file process
  • Added a new peak filter task
  • Added log transformation on Scran deconvolution output data
  • Added option to use gene name or gene ID to filter features based on gene list task
  • Added region length information on differential analysis report on regions
  • Improved creating factorial comparisons on differential analysis dialog
  • Added feature list creation function in data viewer on selected features
  • Minor bug fixes

10.0.21.1026

  • Sped up sparse matrix import
  • Added poscounts normalization method for DESeq2 
  • Added support on .gaf file as gene set library file format
  • Minor bug fixes 

10.0.21.1014

  • Added feature to allow search a list of gene names in volcano plot
  • Added S1 and SUM_MS values to INFO column in Pindel vcf files
  • Added Space ranger task in Flow for hg38, mm10 and hg38-mm10 assembly
  • Improved UMAP speed
  • Improved task graph drawing speed
  • Improved sra file importer
  • Improved h5 importer to handle both 32bit and 64bit values
  • Minor bug fixes 

10.0.21.0929

  • Added Salmon algorithm to compute gene count from fastq files
  • Added Garnett cell type classification function
  • Added support on import and export of h5ad file format on scRNA-seq project
  • Added weighted nearest neighbor algorithm for multimodal single cell datasets analysis
  • Improved speed on user interface interaction
  • Minor bug fixes 

10.0.21.0912

  • Improved PCA dialog when there is only one sample in the project, no need to select split sample option
  • Improved cell number and cell percentage descriptive statistics computation to give more options
  • Improved cell ranger functions to handle CITE-seq data
  • Improved post-alignment QA/QC speed
  • Improved heatmap export to allow entire data after zoom in 
  • Changed TPM normalization method, remove scaling across sample step
  • Added 10X CellRager HDF5 file format option when download single cell data matrix data node
  • Added visualization on enrichment report
  • Minor bug fixes

10.0.21.0816

  • Added a function to allow manually drag&drop to change the order of features/observations on heatmap
  • Minor bug fixes

10.0.21.0801

  • Improvement Kraken on handling samples with multiple files
  • Added report transcript assemblers option in HISAT2
  • Added download option on multiple fastq/bam files associated with one sample to allow download one merged file fastq/bam per sample
  • Minor bug fixes

10.0.21.0723

  • Updated bioproject download link based on the changes on ENA website
  • Minor bug fixes

10.0.21.0718

  • Added function to display both Ensembl gene ID and gene name in differential analysis report
  • Improvement on interface response
  • Minor bug fixes

10.0.21.0707

  • Added Flow version in each task details
  • Allow to change group order by drag and drop directly on the axis on scatter plot
  • Added re-order mode in heatmap to allow to drag and drop observation/feature labels to swap 
  • Added function to display both Ensembl gene ID and gene name in data viewer table
  • Added support on .tsv file format as cell annotation file
  • Added more descriptive statistics to filter cell task report
  • Output STAR fusion in vcf format
  • Improved speed on interface and visualization
  • Minor bug fixes

10.0.21.0621

  • Improve 10X Genomics Visium image annotation to handle multiple samples
  • Added 10X Genomics Cellranger to handle scRNA-seq data from 10X Genomics on human, mouse and human-mouse assemblies
  • Improve PCA computation on memory usage on large datasets
  • Added more functions on metagenomics data analysis 
  • Added STAR fusion function
  • Minor bug fixes

10.0.21.0602

  • Added a sample level box plot on the sctransform task report
  • Added Cell Ranger to process 10X Genomics fastq files and generate count matrix data on hg38, mm10 and hg38-mm10 references
  • Improved library file deletion function – list all projects that using the file
  • Improved hierarchical clustering visualization – allow user to manually adjust dendrogram size
  • Removed log transformation section in PCA and hierarchical clustering dialogs
  • Added more options in the STAR configuration dialog
  • STAR aligner is upgraded to 2.7.8a
  • Added support on Seurat4 objects import (requires R version 4 and above)
  • Minor bug fixes

10.0.21.0509

  • Added a feature of allowing manually type in a list of features to color in scatterplot
  • Added annotate Visium task to add tissue position and image information on 10X Genomics Visium data
  • Added compute biomarker as an independent task in addition to the subtask in any classification task
  • Improved the Seurat3 integration task
  • Enable both Monocle 2 and Monocle 3 in trajectory analysis
  • Added download options for mm39 assembly library files
  • Minor bug fixes

10.0.21.0411

  • Added number of genes for up and down regulation separately in volcano plot
  •  Annotate Visium task to add tissue position and image information on 10X Genomics Visium data
  • Minor bug fixes

10.0.21.0328

  • Added HTSeq quantification method to Microarray data analysis
  • Added BWA method on ERCC in pre-alignment QA/QC
  • Added project statistics information on homepage
  • Improvement Monocle 3 (trajectory analysis) to automatically detect the input data is in log scale or not
  • Minor bug fixes

10.0.21.0302

  • Upgrade trajectory analysis using monocle 3 algorithm
  • Added bubble map shortcut in data viewer
  • Added function to specify gene list in filter feature dialog without creating a list beforehand
  • Added more options in usage report
  • Changed the graph-based clustering nearest neighbor type default from KNN to NN-Descent
  • Improvement on interface
  • Minor bug fixes

10.0.21.0201

  • Added publish cell attributes to project task
  • Scatterplot selection labeling is turned off by default
  • Minor bug fixes

10.0.21.0117

  • Added more options to generate usage report
  • Added more configuration options in BWA-MEM
  • Added download to the user management table
  • Minor bug fixes

10.0.20.1231

  • Added heatmap plot type in data viewer, hierarchical cluster report is in data viewer
  • Added pie chart on visualizing categorical sample/cell annotation
  • Added Harmony algorithm for data transformation
  • Added Scran normalization method
  • Added Seurat 3 integration task
  • Added more options on descriptive statistics task
  • Added filtering capability on task management page
  • Added ability to perform biological interpretation on miRNA data
  • Added similarity matrix task on bulk RNA count matrix data node
  • Added correlation section on task menu and move sample correction, correlation analysis under this menu
  • Added function to import count matrix to allow import multiple files
  • Added function to use sample name to split attribute on single cell data node
  • Improved text importer to handle text file generated from R which has the first column shifted
  • Improved speed on data viewer
  • Improved volcano plot display
  • Improved filter feature task dialog speed and added filter based on feature meta data
  • Changed the default calculation on features in descriptive statistics dialog
  • Changed single cell QA/QC plot to display 4 plots by default
  • Changed DESeq2 only normalization report not using per million scale
  • Changed the per million normalization using the sum of input count instead of aligned read counts
  • Removed the log transformation in tSNE, UMAP and graph-base clustering dialog to reduce confusion
  • Minor bug fixes


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