In projects with multiple data types for each sample such as CITE-Seq, Merge matrices can be used to combine two data nodes with different data types into one data node.
Prerequisites for Merge matrices
- There must samples with more than one type of data in the project
- There must be separate counts data nodes for each data type
Running Merge matrices
- Click the first counts data node
- Click the Pre-analysis tools section of the toolbox
- Click Merge matrices
- Click Select data node to choose the second data node you want to merge (Figure 1)
Figure 1. Picking a second data node to merge
- Double-click the second data node to select it (Figure 2)
Figure 2. Selecting the second matrix
- Click Finish to run
A Merged counts data node is produced (Figure 3).
Figure 3. Merged counts output
The intersection of observations (cells and/or samples) from the two input matrices is included in the merged matrix.
Once two data types have been merged, they can be split using Split matrix.
For a practical example using Merge matrices, please see our tutorial on Analyzing CITE-Seq Data,
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