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Any numerical column from the source gene list can be used to color the gene boxes. While significant p-values indicate a difference between the categories, they give no information about upregulation or downregulation of the pathway. We can overlay fold-change information on the pathway diagram.

• Select Brain vs. Heart: Fold-Change(Brain vs. Heart) from the drop-down menu
  

The pathway diagram now shows fold change for each gene in the pathway included in the gene list (Figure 6). Genes not in the gene list remain black. 

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Opions available include:

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• Select Adherens Junction
• Select View Pathway to open the pathway diagram 

We can use the Project Elements panel to close an open pathway diagram or list.

• Right-click Adherens Junction in the Project Elements panel
• Select Delete from the pop-up menu to close the diagram (Figure 13)