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Any numerical column from the source gene list can be used to color the gene boxes. While significant p-values indicate a difference between the categories, they give no information about upregulation or downregulation of the pathway. We can overlay fold-change information on the pathway diagram.
- Select Brain vs. Heart: Fold-Change(Brain vs. Heart) from the drop-down menu
The pathway diagram now shows fold change for each gene in the pathway included in the gene list (Figure 6). Genes not in the gene list remain black.
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Opions available include:
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- Select Adherens Junction
- Select View Pathway to open the pathway diagram
We can use the Project Elements panel to close an open pathway diagram or list.
- Right-click Adherens Junction in the Project Elements panel
- Select Delete from the pop-up menu to close the diagram (Figure 13)
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