The significant CpG loci detected in the previous step actually form a methylation signature, which we shall now visualise by a heat map.
Select the list (CpG Loci of Interest) spreadsheet in the spreadsheet pane on the left
Select Cluster Based on Significant Genes from the Visualization panel of the Illumina BeadArray Methylation workflow
Select Hierarchical Clustering for Specify Method
Select OK
Verify that 1/list (CpG Loci of Interest) is selected in the drop-down menu
Select Standardize for Expression normalization
Select OK
The heat map will be displayed on the Hierarchical Clustering tab (Figure 1).
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