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• Linux: Ubuntu^® 12.04, Redhat^® 6, CentOS^® 6, or newer
• Mac: OS X Yosemite 10.10 or newer
• 64-bit 2GHz quad-core processor
• 48GB of onboard memory
• 48GB of swap space
• 1TB of storage available for data
• /opt – 100GB of storage available for installation

• A broadband internet connection

Note that some analyses have higher requirements, e.g. to run the STAR aligner on a reference genome of size ~3 GB (such as human, mouse or rat), 16 cores are required. Input sample file size can also impact memory usage, which is particularly the case for TopHat alignments.

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