The data set accompanying this document consists of eight human samples processed by Illumina MethylationEPIC  BeadChip arrays. The data set is taken from a study of DNA methylation in human pluripotent stem cells (hPCS) (Lee et al. Cell Rep 2017) and can be downloaded from Gene Expression Omnibus using the following accession number: GSE95531. To follow this tutorial, download To begin, we will import the 16 .idat files associated with GSE95531 (note that two .idat files are generated for each array) and unzip them on your local computer. A discussion on import of files processed by Illumina’s Genome Studio package can be found in Appendix A.To load the .idat files to Partek Genomics Suite go to thedownloaded from the Gene Expression Omnibus. 

• Go to the Workflows drop down list,

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• select Methylation (Figure 1)

• Select Illumina BeadArray Methylation from the Methylation sub-

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• workflows panel (Figure 2)

• That will open Illumina BeadArray Methylation workflow (Figure

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• 3)

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• Select Import Illumina Methylation Data

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•  to bring up the Load Methylation Data dialog 

• Select Import human methylation 450/850 .idat

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• files (Figure 5)

• Select OK 
• Select Browse... to navigate to the folder you saved the .idat files

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