What is AUCell?

AUCell is a tool to identify cells that are actively expressing genes within a gene list [1]. For each input gene list, AUCell calculates a value for each cell by ranking all genes by their expression level in the cell and identifying what proportion of the genes from the gene list fall within the top 5% (default cutoff) of genes.  This method allows the AUCell value to represent the proportion of genes from the gene list that are expressed in the cell and their relative expression compared to other genes within the cell. Because this is a rank-based method and is calculated for each cell individually, AUCell can be run on raw or normalized data. As an AUCell value is the proportion of genes from the list that are within the top percentile of expressed genes, AUCell values can range from 0 to 1, but may have a more restricted range.  

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