PGS Documentation

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Numbered figure captions
SubtitleTextSetting the method of mapping genes to gene sets
AnchorNameSetting the method of mapping genes to gene sets

 

To setup the GO ANOVA dialogue you must consider all factors that would normally be included in an ANOVA model analyzing gene expression among the samples (Figure 3). Briefly this should include:

  • Experimental factors
  • Factors explaining sample dependence
  • Factors explaining noise

 

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SubtitleTextGO ANOVA setup dialog. Including a factor in the ANOVA model (ANOVA Factors) will identify gene ontology (GO) categories whose expression is different across the genes within the category, by the factor of interest. Including a factor as a Disruption Factor will identify GO categories where the expression of the genes within the category are affected but not uniformly across the genes withing the category. Genes (probesets) can be excluded based on expression levels, to reduce the noise.
AnchorNameSetting up GO ANOVA

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