We will compare the classification (FASN expression) we previously made based on expression levels of the FASN gene. Here, we will compare FASN high and FASN low cells to identify genes and pathways.
Compute biomarkers
- Select the Normalized counts node and choose Compute biomarkers from the Statistics drop-down
- Choose the "FASN expression" attribute
- Do not select Split by sample
- Click Finish
This results in a Biomarkers report.
- Double-click the Biomarkers results node to open the report
The top features are reported for the comparison.
- Download this table with more than 10 features using the Download option
Please click here for more information on differential analysis methods.
Biological Interpretation
Here we are going to perform Gene Set Enrichment on our top 10 features for the FASN high group.
We need to create a list using List management with these 10 genes.
Additional Assistance
If you need additional assistance, please visit our support page to submit a help ticket or find phone numbers for regional support.
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