Click the green plus () icon next to the Variant annotations section header on the library file management page. Alternatively, click the Add library file button and choose Variant annotations from the Library type drop-down list.
 

If you are using a human - hg19 assembly, variant annotation databases from various sources will appear in the Variant annotation drop-down list (Figure 1). Available variant annotation database sources include:

Multiple versions of the above databases are available. For human - hg38, only dbSNP is currently available. This list is periodically updated.

 

Figure 1. For human - hg19, automatic downloads of various variant annotation databases are available from the Partek repository
 
Choose a database from the drop-down list, select the Download variant database radio button and click Create.

If you prefer to add a custom variant annotation database, perhaps from another source or 'gold-standard' validated variants, choose Add variant database from the Variant annotation drop-down list (Figure 2). Name the variant annotation database by typing into the Custom Name box and click Create. Characters such as $ * | \ : " < > ? / % cannot be used in custom names. A variant annotation database can be added from the Partek Flow Server, My Computer or a URL download link. The behavior of each option is similar to when importing a reference sequence (see Adding a Reference Sequence). When browsing for files on the Partek Flow server, only the files with relevant file extensions will be visible (.vcf and various compressed formats).

 

Figure 2. Add a custom variant annotation database