To install or upgrade to the latest version of Partek^® Flow^® software, follow the directions outlined in the Installation Guide.

11.0.24.0414

• Added CellphoneDB task to analyze cell-cell communication process
• Added display transcripts location ability on 10X Genomics Xenium data visualization
• Improved trim adaptor task to be more memory efficient
• Improved file browser when specify a location and click go button, it will scroll to the location on the left panel
• Moved all tasks in Peak analysis section to Region analysis section
• Minor bug fixes 

Latest docker image: registry.partek.com/rtw:24.0414.55

11.0.24.0325

• Added more options for variant filter by fields
• Minor bug fixes 

Latest docker image: registry.partek.com/rtw:24.0325.52

11.0.24.0317

• Added hierarchical cluster analysis task to similarity matrix data node
• Added statistical analysis task to cell descriptive stats
• Minor bug fixes 

Latest docker image: registry.partek.com/rtw:24.0317.49

11.0.24.0311

• Improved convert Seurat to matrix dialog to allow to configure meta data
• Added more options in filter annotated peaks dialog
• Minor bug fixes 

Latest docker image: registry.partek.com/rtw:24.0311.45

11.0.24.0226

• Improved differential analysis report filter option on log2 ratio to allow user to specify a range to filter
• Improved Normalize to housekeeping genes dialog to display both gene ID and gene name
• Added data repository management on Settings page
• Minor bug fixes 

Latest docker image: registry.partek.com/rtw:24.0301.39

11.0.24.0204

• Added long reads aligner minimap2 and pbmm2
• Simplified the Data Viewer configuration dialogs
• Added Scree plot and component loadings table to the PCA report by default
• Added Poisson regression and Negative binomial regression as options in the Differential analysis task
• Minor bug fixes 

Latest docker image: registry.partek.com/rtw:24.0204.33

11.0.24.0102

• Automatically generate spatial report on analysis tab after spatial data import
• Added alt-splicing task option on Salmon's transcript count data node
• Added STARsolo task for 10x Genomics scRNA-seq data
• Updated FreeBayes to v1.3.6
• PCA task default feature filter method is changed to variance from vst 
• Filter peaks task is moved to Filtering section from Peak analysis section on the menu
• Make the enable/disable user account as separate privilege from add user account for admin
• Minor bug fixes 

Latest docker image: registry.partek.com/rtw:24.0102.29

11.0.23.1204

• Enabled MACS peak detection report visualizations in the Data viewer
• Improved the algorithm for the normalize to housekeeping genes task
• Added more gene annotation options in SNV task report
• Fixed the Venn diagram issue on some of the browsers
• Minor bug fixes 

Latest docker image: registry.partek.com/rtw:23.1204.23

11.0.23.1105

• Added search function in Help menu to directly search the content in documentation page
• Added option to choose a number of features to use in PCA computation
• Minor bug fixes 

Latest docker image: registry.partek.com/rtw:23.1105.16

11.0.23.1023

• Improved differential analysis report layout
• Add impute missing value task
• Minor bug fixes 

Latest docker image: registry.partek.com/rtw:23.1023.14

11.0.23.1009

• Improved pre-alignment QC report
• Fixed differential analysis report table download issue
• Minor bug fixes 

Latest docker image: registry.partek.com/rtw:23.1009.11

11.0.23.0918

• The user interface now boasts a modern appearance
• Enhanced the import wizard for greater intuitiveness and user-friendliness
• Added support for SomaLogic ADAT bulk protein data
• Improved the file browser for fast access to recent server uploads 
• Bolstered file protection to prevent accidental deletions when used by other projects
• Added support for the 10x Genomics Xenium platform 
• Introduced support for the Nanostring CosMx platform
• Added a new task for Correlation analysis between different assays
• Improved scatterplot selection with a handy painting mode 
• Added the ability to display a high resolution Visium image with a new Spatial imaging report task for quick viewing
• Added a manual alignment option for tissue image visualization 
• Streamlined the import process for multiple files per sample, e.g. import all 3 sparse matrix (feature-barcode-matrix) files per sample for all samples at one time 
• Added more available information on the Annotated region report
• Improved the Seurat object conversion to be more intuitive
• Added a more detailed report to the Adapter trimming task
• Creating pseudobulk data by pooling single cells has been made easier with increased functionality
• Optimized the differential analysis dialogs for improved usability 
• Changed the default normalization method for bulk RNA-Seq data to Median ratio (DESeq2)
• Improved the Detect fusions and Trim bases tasks to be more intuitive 
• Allowed the Single-cell QA/QC task to be performed on individual samples
• Minor bug fixes 

Latest docker image: registry.partek.com/rtw:23.0918.1

Archived Release Notes -- Partek Flow 10