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SC transform task performs the normalization method of R package sctransform variance stabilizing normalization proposed in [1]. The task's interface follows that of SCTransform() function in R
We recommend performing sctransform normalization on single cell row count data node. Select SCTransfrom task in Normalization and scaling section on the pop-up menu to invoke the dialog (Figure 1)
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- Christoph Hafemeister, Rahul Satija Normalization and variance stabilization of single-cell RNA-seq data using regularized negative binomial regression. https://doi.org/10.1101/576827
- SCTransform() documentation https://www.rdocumentation.org/packages/Seurat/versions/3.1.4/topics/SCTransform
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