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The BED file will open as a new spreadsheet (Figure 5). 

• Change the spreadsheet name to UCSC CpG Island Annotation and save it 

For this region list, you can also calculate the average beta values for the probes in each island per sample and detect differential methylated CpG islands regions. Detailed information on how to get average beta value for each CpG can be found from the in the Determining the average values for a region list section of  Help>On-line Tutorials>User Guides> List.  

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