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To explore more, the task of Explore CellPhoneDB results allows users to filter CellPhoneDB results by specifying the cell type pairs and genes of interest.  See Figure 4 on how to run the task. After clicking the CellPhoneDB data node (Figure 4a), one will find there's only task triggered under Exploratory analysis menu (Figure 4b).  Its GUI is also simple and easy to understand. For each option, the grey colored description explains more details (Figure 2).  If the dataset working on is single cell RNA-Seq, no Micro environment file is needed. However, if the dataset is spatial, most likely you would like to provide the Micro environment file because of its spatial contents. By default 0.10 will be used as threshold to select which cells are used for the analysis in the cluster. However, the number could be adjusted manually or typed in directly.  Simply click Genes of interest are data dependent and usually come from published results of similar studies or the differential gene analysis between conditions (eg, cancer patient vs healthy controls).  Once set up, click the Finish button if you want to run submit the task as defaultjob.

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